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cdk8 inhibitor bi 1347  (MedChemExpress)


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    MedChemExpress cdk8 inhibitor bi 1347
    Cdk8 Inhibitor Bi 1347, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 6 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/cdk8+inhibitor+bi+1347/BI-1347/bio_rxiv__2025__10__08__681188-302-12-15
    Average 94 stars, based on 6 article reviews
    cdk8 inhibitor bi 1347 - by Bioz Stars, 2026-09
    94/100 stars

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    cdk8 inhibitor bi 1347  (MedChemExpress)
    94
    MedChemExpress cdk8 inhibitor bi 1347
    Cdk8 Inhibitor Bi 1347, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/cdk8+inhibitor+bi+1347/BI-1347/bio_rxiv__2025__10__08__681188-302-12-15
    Average 94 stars, based on 1 article reviews
    cdk8 inhibitor bi 1347 - by Bioz Stars, 2026-09
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    bi-1347 (cdk8/19 inhibitors)  (Boehringer Ingelheim)
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    Boehringer Ingelheim bi-1347 (cdk8/19 inhibitors)
    Efficacy of combining daily oral treatment of the <t> CDK8/19 </t> inhibitor BI-1347 (10 mg/kg) with the anti-murine PD-1 antibody (10 mg/kg, intraperitoneal, twice weekly) in the MC-38 murine syngeneic mouse model. Combination of anti-PD-1 plus BI-1347 leads to significant enhanced anti-tumor response compared to both BI-1347 (p=0.0317) and anti-PD-1 (p=0.0476) in monotherapy (Mann Whitney, one tailed, non-adjusted).
    Bi 1347 (Cdk8/19 Inhibitors), supplied by Boehringer Ingelheim, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/cdk8+inhibitor+bi+1347/bi+1347/pmc07661742-62-1-11
    Average 90 stars, based on 1 article reviews
    bi-1347 (cdk8/19 inhibitors) - by Bioz Stars, 2026-09
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    Efficacy of combining daily oral treatment of the CDK8/19 inhibitor BI-1347 (10 mg/kg) with the anti-murine PD-1 antibody (10 mg/kg, intraperitoneal, twice weekly) in the MC-38 murine syngeneic mouse model. Combination of anti-PD-1 plus BI-1347 leads to significant enhanced anti-tumor response compared to both BI-1347 (p=0.0317) and anti-PD-1 (p=0.0476) in monotherapy (Mann Whitney, one tailed, non-adjusted).

    Journal: Molecular cancer therapeutics

    Article Title: Selective and potent CDK8/19 inhibitors enhance NK cell activity and promote tumor surveillance

    doi: 10.1158/1535-7163.MCT-19-0789

    Figure Lengend Snippet: Efficacy of combining daily oral treatment of the CDK8/19 inhibitor BI-1347 (10 mg/kg) with the anti-murine PD-1 antibody (10 mg/kg, intraperitoneal, twice weekly) in the MC-38 murine syngeneic mouse model. Combination of anti-PD-1 plus BI-1347 leads to significant enhanced anti-tumor response compared to both BI-1347 (p=0.0317) and anti-PD-1 (p=0.0476) in monotherapy (Mann Whitney, one tailed, non-adjusted).

    Article Snippet: 2), BI-1347 (CDK8/19 inhibitors) and BI-8382 (SMAC mimetic) were synthesized at Boehringer Ingelheim.

    Techniques: MANN-WHITNEY, One-tailed Test, Control